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4s3™ Semi-Automatic Sheet Heat Sealer 

The 4s3™ is a semi-automatic thermal sealer which is compatible with a wide range of seals and plates of differing designs and heights.

With variable temperature and time settings, sealing conditions are easily optimised to produce a 100% seal, eliminating sample loss.

Plate and seal are placed on the holder, the "Operate" button pressed and the drawer automatically closes.  The sealing process is controlled by an electric mechanism. This unique feature eliminates operator variation, giving a consistent seal every time and reducing the damage caused to microplates by over-sealing.



Real Time Display


The rapid heating element allows for a quick start up within minutes.

The temperature is displayed in real time so that the heating up process can be monitored.


Energy Saving Functions


 When the unit is left idle it automatically switches into standby mode, during which the temperature of the heating element is reduced to 60°C to save energy. When the sealer is left idle for longer periods it switches off automatically for added safety. The times at which the unit switches into standby and switch off modes can be adjusted to suit the user’s needs.


Adapters and Sealing Aids


The 4s3™ employs a unique and cost saving adapter system. Deep well plates and most other skirted plates can be sealed on the standard plate carrier (4ti-0615, supplied with the unit). For all 96 well PCR plates an additional plate carrier (4ti-0625, optional extra) must be used. Both plate carriers can also be combined for easier handling of shallow well plates such as 384 well PCR plates.

For better sealing of those films which have a tendency to curl, 4titude offer sealing aids. A weighted platen (4ti-0602) for use with deep well blocks is provided with the unit and a sealing frame for use with all other plate designs is supplied when ordering the optional 4ti-0625 adapter.



RS-232 Port for Automation Integration


The 4s3™ has an RS-232 port to enable it to be integrated into most automated systems.



Plate Formats


The following plate formats can be used with an appropriate holder:

  • SBS standard polypropylene & polystyrene plates & deepwell blocks
  • PCR plates including skirted, semi-skirted and non-skirted formats



Large Range of Heat Sealing Films & Foils


4titude® offer the largest range of sealing films and foils.  To find out more information on our heat seal range, click here.


4s3™ operation in 6 easy steps!

4s3 step 14s3 step 34s3 step 5
4s3 step 24s3 step 44s3 step 6


• Automatic sealing process for

  unmatched sealing consistency

• Variable temperature and time

  settings for easy optimisation

  of sealing conditions.

• Simple, single button operation.

• Rapid heating element for fast

  start up.

• Real-time temperature display.

• Auto stand-by function to

  save energy.

• Auto switch off function for

  added safety.

• Compatible with a wide variety

  of consumables.

• RS-232 serial port enables

  full integration with robot

  automation systems.

Full range of heat seals


• Small footprint.

• Low temperature sealing for

  use with adhesive seals.

technical data

Weight: 9kg

Dimensions: H 310 x D 275 x W 181

Voltage: 110/230V

Power: 300W

Sealing Temperature: 60-200°C





4s3™ heat sealer, incl. universal power supply, power cord, manual, standard plate adapter (4ti-0615) and weighted seal platen (4ti-0602)


Sealing Accessories and Tools






Adapter for deep-well, 384-well and skirted 96-well plates

Adapter for Roche 1536-well PCR plate

Weighted seal platen to hold down sealing sheets that have a tendency to curl

Adapter for 96-well PCR plates, includes sealing frame (4ti-0612)

Sealing frame for use with 4ti-0625 adapter

1 Adapter

1 Adapter

1 Platen

1 Adapter

1 Frame

*These items are included with the 4s3™ heat sealer

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