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The a4S Automatic Roll Heat Sealer provides the perfect solution for automated heat sealing of medium to high-throughput or full automation applications.
Available in the following colours
The main advantage of the a4S is that it does not require an air supply, which gives it the flexibility to be used on standard lab benches as a stand-alone unit, or integrated within a robotic set‑up. The sealer’s rapid heating element enables a fast start-up, and the stand-by function saves energy when the unit is not in use.
The a4S sealer is compatible with a wide range of SBS footprint plates, including all PCR plate formats from 96 well to 1536 well, assay plates, deep well storage plates and microplates. Varying plate heights, from 3mm to 60mm can be accommodated with minimal adjustments of the instrument. Plates are presented in the portrait format and the plate position on the shuttle allows good access for robotic integration.
Rolls with a width of between 75-85 mm can be loaded in either of two roll positions, depending on roll length and available space, enabling the entire instrument to fit under the gantree of most liquid handling robots.
The width and length of the applied seals are set to precisely cover an SBS footprint plate without interfering with plate stacking. The seal position can be adjusted to give an overhang at one end of the plate to facilitate ease of seal removal.
All 4titude® instruments are compliant with SiLA standards for rapid integration of automated systems (www.sila-standard.org). This means they can be "plug and play" connected with other instruments, such as readers, robotic arms and liquid handlers, to give a custom automated system without the need to write expensive custom drivers. The a4S heat sealer is extremely versatile leaving you the freedom to expand and configure your systems such as adding robotic plate handling.
• Full communication protocol available - Operate the instrument and record sealing conditions for each seal using the RS232 communication port
• SiLA compatible - Quick and easy integration with other SiLA compliant devices using the SiLA driver (available at extra cost, please see ordering information).
Heat Sealing is the gold standard method for plate sealing. Not only does it minimise sample loss but also maximises sample security for PCR, qPCR, storage, and other applications.
Three typical applications for automated heat sealing are outlined below. Please Click Here to see our entire portfolio of heat seals.
qPCR - Reduce evaporation and save money
The optimised sealing performance of the a4S heat sealer prevents reagent volume loss by evaporation.
Up to a fivefold reduction in the costs of sealing can be achieved when heat sealing with the a4S compared to using caps or adhesive seals - Reliable qPCR results and significant reagent savings.
Cell assays and Cell culture - Increase cell viability and assay performance
Heat sealing is the optimal method for cell based assay plates and cell culture plates. It is a proven method for compound storage, particularly in protective gases such as Argon and CO₂.
Sample Storage - Strongest resistance against organic solvents
Essential requirements for long-term storage include maintaining sample integrity and minimising the risks of sample degradation.
4titude® stocks one of the widest ranges of sealing solutions for varying applications. We can also design and manufacture custom solutions for specific non-standard sealing requirements. This service includes custom sealer blocks for the a4S and 4S3 heat sealers as well as custom size and specification seal material. Contact us at firstname.lastname@example.org.
a4S Product Flyer.pdf
a4S Sealing Reference Sheet.pdf
a4S Technical Drawing.pdf
a4S Operation Manual.pdf
a4S Quick User Guide - English.pdf
a4S Quick User Guide - French.pdf
Heat Sealing Consumables Comparison & Instrument Compatibility Table
Heat Seal Selection Guide.pdf
*These items are included with the a4S heat sealer (Code 4ti-0665)
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